Overexpressing PHD3 limits FAO via regulation of ACC2 and consequently impedes leukemia cell proliferation

Overexpressing PHD3 limits FAO via regulation of ACC2 and consequently impedes leukemia cell proliferation

Overexpressing PHD3 limits FAO via regulation of ACC2 and consequently impedes leukemia cell proliferation. our understanding of tumor metabolism is usually incomplete because numerous tumors are FDG-PET unfavorable (Long and Smith, 2011; Ono et al., 2007), suggesting many cancers utilize alternate carbon sources. Multiple malignancy 

T

T

T. addressed the legislation of autophagy through the pathophysiology of T1D. In this scholarly study, we record that cytokines activate the AMPK-ULK-1 pathway while inhibiting mTORC1, which stimulates autophagy activity within an ER stress-dependent way. Alternatively, time-course evaluation of LC3-II deposition in autophagosomes uncovered that