IMAC has also been used to isolate histidine-tagged recombinant proteins, DNA-based aptamers, and phosphopeptides [131,278,282,284,285]. Boronic acid and its derivatives represent another class of non-biological binding agents that have been utilized in affinity chromatography [286C289]. offers strong binding with human being IgG and IgA [162,163]. Mixtures of immunoglobulin-binding proteins or recombinant forms such as protein…

Shaikh cultures. or cord blood is governed primarily by number of stem and progenitor cells in the infused product1,2. Early Engraftment is associated with fewer complications, lower overall treatment costs, and a higher potential for a successful transplant. Many times stem cell yield is not sufficient for autologous and allogeneic transplants. In autologous transplant setting,…

While advances in pharmacologic options for HIV treatment have reduced the incidence and severity of ART-induced adipocyte toxicity (principally mitochondrial DNA [mtDNA] depletion and altered gene expression), the persistence of viral proteins in circulation and locally within adipose tissue impairs adipocyte maturation and activity despite suppression of plasma viremia on therapy (2, 7, 29, 57,…